Project

NeuroTidal Diagnostics 

Parkinson’s disease (PD) affects about 10 million people worldwide, and cases are expected to double by 2050. Yet there is still no cure. Because we lack objective tools to monitor disease biology, it is difficult to assess new treatments, and diagnosis often arrives after irreversible brain damage has occurred.
Our answer to this problem is the FibrilRuler Test: a simple biomarker assay that measures amyloid fibrils, the key pathological hallmark of PD, directly in blood or spinal fluid. We detect their presence and quantify their properties to enable earlier detection and more accurate monitoring.

Our goal is to bridge the gap in PD diagnostics. Through the Biotech Booster program, we will validate the assay on retrospective patient samples and advance FibrilRuler to a clinic-ready test. By tracking PD earlier and more objectively, the assay supports therapy development, helps patients receive the right care sooner, and reduces the overall burden on healthcare systems.

Project team

Françoise Dekker (project lead), Pleun van Veghel, Prof. Dr. Stefan Rüdiger

Project Number

BIOB25014

Year granted

2025

Status

Ongoing

Applicant

Utrecht University

Funding

€ 200.000

Sector/Industry

Health & Pharma

SDG's

Good health and well-being (SDG 3)

Thematic Cluster

TC4: Diagnostics and Services

Level

Level 1
Molecuul

2025

Year granted

Utrecht University

Applicant

€ 200.000

Project funded

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Citaat

Biotech Booster helps us through funding and by providing us with a network to validate where we can make the best impact with our new analysis device.

Biotechnology netherlands

Carlos de Lannoy

Constellate

Citaat

What we look forward to most is leveraging the extraordinary network of Biotech Booster that we need to get foot in the market, get know-how, and understanding the competitive field which is necessary for setting up successful operations.

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Pim Schaasberg & Martin Pabst

ProteoT

Moleculen

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