The problem: Antibiotic resistance is a growing global health threat, causing 1.3 million deaths annually, but no new classes of antibiotics have been developed since 1984. Bacteria combat antibiotics by forming protective biofilms, reducing uptake of antibiotics, enzymatically degrading antibiotics, or actively pumping them out through efflux pumps. Without a new strategy for antibiotics delivery, it is only a matter of time until antimicrobial resistance develops against new antibiotics.
Our technology and solution: Our team has developed unique nanoparticles that could aid antibiotics and reduce resistance. Our nanoparticles can be readily prepared on a large scale.
Our societal impact: Our technology reduces the burden of antimicrobial resistance and avoids overuse of antibiotics. Efficient antibiotic nanoparticles can be employed to fight a variety of bacterial infections, ranging from veterinary medicine to human healthcare, as well as from superficial infections to severe multidrug-resistant infections.
