Project

Biotechnology netherlands

Next generation formulations for RNA

Liporyx is developing a bioinspired lipid-like polymer technology to safely and specifically deliver nucleic acid therapeutics to diverse cell types in the body. Most RNA therapeutics do not traverse the body well and are typically removed from circulation by the liver, limiting their effectiveness for many diseases. A highly versatile drug delivery system lies at the heart of Liporyx, enabling the precise delivery of therapeutic payloads directly into the cytosol of targeted cells. We are using modular approach to engineer this platform, with the aim of unlocking the vast array of therapeutic targets which are currently undruggable using existing formulations.

This research project will allow for the further demonstration of the platform technologyā€™s benefits in preclinical models, validation with therapeutic RNA targeting immune checkpoint receptors for cancer immunotherapy, and for pitching to potential investors. We are on a mission to drive forward RNA therapeutics, unlocking their potential to transform the pharmaceutical industry landscape and enhance the lives of millions of patients worldwide.

Project team

Alexander Cook

Project Number

BIOB24067

Year granted

2024

Applicant

Eindhoven University of Technology

Funding

ā‚¬ 200.000

Sector/Industry

Health & Pharma

SDG's

Good health and well-being (SDG 3)
Industry, innovation and infrastructure (SDG 9)

Thematic Cluster

TC3: ATMPs, Biopharmaceuticals & Associated Enabling Technologies
Molecuul

2024

Year granted

Eindhoven University of Technology

Applicant

ā‚¬ 200.000

Project funded

Introducing Jasper Dijkstra

In this series ā€œMeet the people behind Biotech Boosterā€ we introduce you to the passionate people who are involved in

Introducing Jasper Dijkstra

Introducing Bob Ignacio

In this series ā€œMeet the people behind Biotech Boosterā€ we introduce you to the passionate people who are involved in

Introducing Bob Ignacio

Introducing Eva Moreno Iglesias

In this series ā€œMeet the people behind Biotech Boosterā€ we introduce you to the passionate people who are involved in

Introducing Eva Moreno Iglesias

Event recap: Celebrating Project kick-offs

On December 9th and 10th we celebrated the kick-offs of the 50 Proof-of-Principle (Level 1) projects that joined the Biotech

Event recap: Celebrating Project kick-offs

Press release (Dutch) : Nederlandse Biotech-uitvindingen klaar voor race naar tastbare toepassing

Het ministerie van Onderwijs, Cultuur & Wetenschap (OCW) heeft aan 54 biotechnologische uitvindingen van Nederlandse bodem een financiƫle injectie toegekend,

Press release (Dutch) : Nederlandse Biotech-uitvindingen klaar voor race naar tastbare toepassing

Join the Pool of Entrepreneurs: open invitation

In our program we are bringing seasoned entrepreneurs and starting (academic) teams actively together to better align the scientific basis

Join the Pool of Entrepreneurs: open invitation
Citaat

Biotech Booster helps us through funding and by providing us with a network to validate where we can make the best impact with our new analysis device.

Biotechnology netherlands

Carlos de Lannoy

Constellate

Citaat

What we look forward to most is leveraging the extraordinary network of Biotech Booster that we need to get foot in the market, get know-how, and understanding the competitive field which is necessary for setting up successful operations.

Biotechnology netherlands

Pim Schaasberg & Martin Pabst

ProteoT

Moleculen

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