Project

Biotechnology netherlands

Super Mendelian Microfactories

Yeast has been used for centuries to make bread, beer, and wine. Since the late 20th century, it has also been used to produce important medicines like insulin. For the bioeconomy, where biological processes create sustainable products, yeast can be harnessed to make a wide range of products, from flavours and fragrances to materials and food ingredients. The biggest challenge, however, is reprogramming the DNA of yeast, a process that is typically slow and costly. We have developed a technology, that makes use of CRISPR-Cas, a powerful tool often compared to “Ctrl-F” and “Ctrl-X” for DNA. With this technology, the DNA of yeast can be modified exponentially faster and at a lower cost, enabling quicker production and making bio-based solutions more accessible and efficient.

With this Biotech Booster project, we will further develop the technology and apply it to a relevant industrial challenge by improving a yeast strain for microbial production. Alongside the technical development, this project will also involve business development activities to build a solid business case to support the commercial potential of the technology.

Thanks to Biotech Booster, the platform can be further developed and optimized, allowing for impactful contributions to more sustainable microbial production and supporting the growth of the bioeconomy.

Project team

Carina Nieuwenweg, María Suárez Diez, Stefan Hoffmann, Melvin Siliakus, Nico Claassens, Raymond Staals

Project Number

BIOB24047

Year granted

2024

Status

Ongoing

Applicant

Wageningen University & Research

Funding

€ 200.000

Sector/Industry

Manufacturing & Production, Agri- & Horticulture, Food & Beverages, Health & Pharma

SDG's

Industry, innovation and infrastructure (SDG 9)
Responsible consumption and production (SDG 12)

Thematic Cluster

TC1: Industrial Biotechnology & Production

Level

Level 1
Molecuul

2024

Year granted

Wageningen University & Research

Applicant

€ 200.000

Project funded
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