Happy Bar

At the core of our initiative is the urgent need to tackle the rising global prevalence of mental health disorders, including depression and anxiety. These conditions not only diminish individuals’ quality of life but also place a heavy financial burden on society. Recent studies have demonstrated a strong connection between the gut microbiome and mental […]

KETO-X Minerals

Our unilateral diet has resulted in a deficiency of specific elements needed for the well-functioning of the human body. Especially magnesium is low in our processed food. It has been recognized that magnesium plays an important role in cognition and positively affects sleep and calmness (anti-stress). Commercially available magnesium supplements (magnesiumoxide, and magnesium citrate glycerophosphate, […]

Silver Bullet

At Leiden University, and our spin-off company GenLumina, we are working on innovative ways to treat cancer. We develop tiny, DNA-based structures that can target and treat cancer cells with incredible precision. Imagine an automated treatment device that detects cancer on or in the body, and delivers light to effectively treat it with minimal side […]

PanaxTX

Corticosteroid drugs, such as dexamethasone and prednisolone, are among the most prescribed drugs in the world. These immune-suppressive drugs are very effective against inflammatory and auto-immune diseases, such as asthma, psoriasis, inflammatory bowel disease and rheumatoid arthritis. However, their use is limited by their side effects, which are severe and include osteoporosis, elevated blood sugar […]

MimeCure

Chronic obstructive pulmonary disease (COPD) is a prevalent and deadly lung disease (third leading cause of death worldwide), caused mainly by tobacco smoke and air pollutants. With approximately 300 million patients worldwide, the economic burden is projected to reach INT$ 4.326 trillion by 2050. The key problem underlying COPD pathogenesis is increased tissue destruction and […]

Prolispot

Detection of rare dividing cells in blood samples and complex cell mixtures is currently not feasible with existing techniques, which are insufficiently sensitive for biomedical applications. This is critical for applications such as quantifying proliferating cancer and T cells, determining vaccine efficacy, and measuring tumor immune responses or emerging pathogens. Existing methods struggle to detect […]

PRADA

The ongoing global rise of antimicrobial-resistance (AMR) is forcing healthcare to rely more frequently on ‘last-resort’ antibiotics with higher risks for patients. The polymyxins are among the most prevalent last resort antibiotics as they are increasing used for the treatment of infections caused by multi drug resistant Gram-negative pathogens. A range of acute toxicities are […]

Nuna Bioscience

Surgical repair of critically sized bone defects occurs 2 million times per year. Those defects are typically filled with autologous bone implants. However, due to the inability to maintain the viability of such large bone implants, their essential functionality for tissue healing and regeneration is largely lost, leading to failure of the bone healing process. […]

Ninetac

Colorectal cancer (CRC) is a common and often deadly disease. Every year 1.9 Mio. cases and over 900 000 deaths are registered globally. While surgery remains the primary treatment option, radiotherapy and chemotherapy are frequently necessary but come with significant drawbacks. These systemic treatments are toxic to all cells alike, leading to severe side effects […]